Doublecortin Knockout Mice Show Normal Hippocampal-Dependent Memory Despite CA3 Lamination Defects

Mutations in the human X-linked doublecortin gene (DCX) cause major neocortical disorganization associated with severe intellectual disability and intractable epilepsy. Although Dcx knockout (KO) mice exhibit normal isocortical development and architecture, they show lamination defects of the hippoc...

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Autori principali: Germain, Johanne, Bruel-Jungerman, Elodie, Grannec, Gael, Denis, Cécile, Lepousez, Gabriel, Giros, Bruno, Francis, Fiona, Nosten-Bertrand, Marika
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779246/
https://ncbi.nlm.nih.gov/pubmed/24073232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074992
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