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HIV-1 Tat Protein Induces the Production of IDO in Human Monocyte Derived-Dendritic Cells through a Direct Mechanism: Effect on T Cells Proliferation

During HIV-1 infection, an increase of indoleamine 2,3 dioxygenase (IDO) expression, and dendritic cells (DC) dysfunction were often associated with AIDS disease progression. In this work, we investigated the effect of HIV-1 Tat protein on the expression of IDO, in MoDCs. We show that Tat induces ID...

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Bibliografiske detaljer
Main Authors: Planès, Rémi, Bahraoui, Elmostafa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779232/
https://ncbi.nlm.nih.gov/pubmed/24073214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074551
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