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DNA damage tolerance: a double-edged sword guarding the genome

Preservation of genome integrity is an essential process for cell homeostasis. During the course of life of a single cell, the genome is constantly damaged by endogenous and exogenous agents. To ensure genome stability, cells use a global signaling network, namely the DNA damage response (DDR) to se...

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Detalhes bibliográficos
Main Authors: Ghosal, Gargi, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779140/
https://ncbi.nlm.nih.gov/pubmed/24058901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2013.04.01
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