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Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability

The Akt family of serine/threonine protein kinases are key regulators of multiple aspects of cell behaviour, including proliferation, survival, metabolism, and tumorigenesis. Growth-factor-activated Akt signalling promotes progression through normal, unperturbed cell cycles by acting on diverse down...

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Detalhes bibliográficos
Main Authors: Xu, Naihan, Lao, Yuanzhi, Zhang, Yaou, Gillespie, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317191/
https://ncbi.nlm.nih.gov/pubmed/22481935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/951724
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