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Do t-tubules play a role in arrhythmogenesis in cardiac ventricular myocytes?

The transverse (t-) tubules of mammalian ventricular myocytes are invaginations of the surface membrane. The function of many of the key proteins involved in excitation–contraction coupling is located predominantly at the t-tubules, which thus form a Ca(2+)-handling micro-environment that is central...

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Autors principals: Orchard, C H, Bryant, S M, James, A F
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779108/
https://ncbi.nlm.nih.gov/pubmed/23652596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.254540
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