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A Novel Kernel for Correcting Size Bias in the Logistic Kernel Machine Test with an Application to Rheumatoid Arthritis

OBJECTIVES: The logistic kernel machine test (LKMT) is a testing procedure tailored towards high-dimensional genetic data. Its use in pathway analyses of GWA case-control studies results from its computational efficiency and flexibility of incorporating additional information via the kernel. The ker...

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Detalhes bibliográficos
Main Authors: Freytag, Saskia, Bickeböller, Heike, Amos, Christopher I., Kneib, Thomas, Schlather, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779069/
https://ncbi.nlm.nih.gov/pubmed/23466369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000347188
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