Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is associated with altered physiological characteristics and gene expression in the placenta. DNA methylation is a relativel...

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Hauptverfasser: Blair, John D., Yuen, Ryan K.C., Lim, Brendan K., McFadden, Deborah E., von Dadelszen, Peter, Robinson, Wendy P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779005/
https://ncbi.nlm.nih.gov/pubmed/23770704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gat044
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