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Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta

Placental cortisol is inactivated in normotensive pregnancies, but is frequently present in pre-eclampsia associated placentae. Since glucocorticoids are strongly associated with the programming of long-term health, we assessed DNA methylation of genes involved in cortisol signalling and bioavailabi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hogg, Kirsten, Blair, John D., McFadden, Deborah E., von Dadelszen, Peter, Robinson, Wendy P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647069/
https://ncbi.nlm.nih.gov/pubmed/23667551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062969
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