DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia

Preeclampsia and intrauterine growth restriction (IUGR) are two of the most common adverse pregnancy outcomes, but their underlying causes are mostly unknown. Although multiple studies have investigated gene expression changes in these disorders, few studies have examined epigenetic changes. Analysi...

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Bibliographic Details
Main Authors: Yuen, Ryan KC, Peñaherrera, Maria S, von Dadelszen, Peter, McFadden, Deborah E, Robinson, Wendy P
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987406/
https://ncbi.nlm.nih.gov/pubmed/20442742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.63
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