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Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) catalyzes the hydrolysis of the phosphodiester linkage between the DNA 3′ phosphate and a tyrosine residue as well as a variety of other DNA 3′ damaged termini. Recently we have shown that Tdp1 can liberate the 3′ DNA phosphate termini from apurinic/apyrimidini...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Editions Scientifiques Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778944/ https://ncbi.nlm.nih.gov/pubmed/22522093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2012.04.004 |
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