The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain

The plant cytotoxin ricin enters mammalian cells by receptor-mediated endocytosis, undergoing retrograde transport to the ER (endoplasmic reticulum) where its catalytic A chain (RTA) is reductively separated from the holotoxin to enter the cytosol and inactivate ribosomes. The currently accepted mod...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, J. Michael, Hartmann-Petersen, Rasmus, Roberts, Lynne M., Spooner, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778710/
https://ncbi.nlm.nih.gov/pubmed/23617410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130133
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi