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Effects of intratumoral administration of a hyaluronan-cisplatin nanoconjugate to five dogs with soft tissue sarcomas

OBJECTIVE: To determine the effects of intratumoral injection of a hyaluronan-cisplatin nanoconjugate on local and systemic platinum concentrations and systemic toxicosis. ANIMALS: 5 dogs with spontaneous soft tissue sarcomas (STSs). PROCEDURES: For each dog, approximately 1.5 mL of hyaluronan nanoc...

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Detalhes bibliográficos
Main Authors: Venable, Rachel O., Worley, Deanna R., Gustafson, Daniel L., Hansen, Ryan J., Ehrhart, E. J., Cai, Shuang, Cohen, Mark S., Forrest, M. Laird
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778682/
https://ncbi.nlm.nih.gov/pubmed/23176425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2460/ajvr.73.12.1969
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