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Loss of calcineurin in the spinal dorsal horn contributes to neuropathic pain and intrathecal administration of the phosphatase provides prolonged analgesia

Calcineurin (protein phosphatase 3) regulates synaptic plasticity in the brain. The development of neuropathic pain appears dependent upon some of the same mechanisms that underlie brain synaptic plasticity. In this study we examined whether calcineurin regulates chronic constriction injury (CCI)-el...

詳細記述

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書誌詳細
主要な著者: Miletic, Gordana, Lippitt, Jennifer A., Sullivan, Kristine M., Miletic, Vjekoslav
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778136/
https://ncbi.nlm.nih.gov/pubmed/23778296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.06.019
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