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The nicotine-mediated decline in L-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release

L-dopa-induced dyskinesias (LIDs) are a side effect of Parkinson’s disease therapy that is thought to arise, at least in part, because of excessive dopaminergic activity. Thus, drugs that regulate dopaminergic tone may provide an approach to manage LIDs. Our previous studies showed that nicotine tre...

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Bibliographic Details
Main Authors: Bordia, Tanuja, McIntosh, J. Michael, Quik, Maryka
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778041/
https://ncbi.nlm.nih.gov/pubmed/23373725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12179
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