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A Computational Model for Histone Mark Propagation Reproduces the Distribution of Heterochromatin in Different Human Cell Types

Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which consists of a histone octamer with DNA wrapped around it. Histone proteins are implicated in the regulation of eukaryote genes and they carr...

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Detalhes bibliográficos
Main Authors: Schwämmle, Veit, Jensen, Ole Nørregaard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777982/
https://ncbi.nlm.nih.gov/pubmed/24069233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073818
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