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Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2 (ABCG2) is an ATP-binding cassette (ABC) transporter identified as a molecular cause of multidrug resistance (MDR) in diverse cancer cells. BCRP physiologically functions as a part of a self-defense mechanism for the o...

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Bibliographic Details
Main Authors: Nakanishi, Takeo, Ross, Douglas D.
Format: Artigo
Language:Inglês
Published: Sun Yat-sen University Cancer Center 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777471/
https://ncbi.nlm.nih.gov/pubmed/22098950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10320
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