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Nonmetabolic functions of pyruvate kinase isoform M2 in controlling cell cycle progression and tumorigenesis

Pyruvate kinase catalyzes the rate-limiting final step of glycolysis, generating adenosine triphosphate (ATP) and pyruvate. The M2 tumor-specific isoform of pyruvate kinase (PKM2) promotes glucose uptake and lactate production in the presence of oxygen, known as aerobic glycolysis or the Warburg eff...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Lu, Zhimin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Sun Yat-sen University Cancer Center 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777463/
https://ncbi.nlm.nih.gov/pubmed/22200182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10446
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