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HLA-F complex without peptide binds to MHC class I protein in the open conformer form

HLA-F has very low levels of polymorphism in humans and is highly conserved among primates suggesting a conserved function in the immune response. In this study we probed the structure of HLA-F on the surface of B-LCLs and activated lymphocytes by direct measurement of peptide binding of native HLA-...

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Detalhes bibliográficos
Main Authors: Goodridge, Jodie P., Burian, Aura, Lee, Ni, Geraghty, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777411/
https://ncbi.nlm.nih.gov/pubmed/20483783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000078
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