A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

The development of tools for efficient targeting of antigens to antigen presenting cells is of great importance for vaccine development. We have previously shown that fusion proteins containing antigens fused to the extra domain A from fibronectin (EDA), an endogenous TLR4 ligand, which targets anti...

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Bibliographische Detailangaben
Hauptverfasser: Arribillaga, Laura, Durantez, Maika, Lozano, Teresa, Rudilla, Francesc, Rehberger, Federico, Casares, Noelia, Villanueva, Lorea, Martinez, Marta, Gorraiz, Marta, Borrás-Cuesta, Francisco, Sarobe, Pablo, Prieto, Jesús, Lasarte, Juan José
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777173/
https://ncbi.nlm.nih.gov/pubmed/24093105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/864720
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