A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

The development of tools for efficient targeting of antigens to antigen presenting cells is of great importance for vaccine development. We have previously shown that fusion proteins containing antigens fused to the extra domain A from fibronectin (EDA), an endogenous TLR4 ligand, which targets anti...

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Bibliographic Details
Main Authors: Arribillaga, Laura, Durantez, Maika, Lozano, Teresa, Rudilla, Francesc, Rehberger, Federico, Casares, Noelia, Villanueva, Lorea, Martinez, Marta, Gorraiz, Marta, Borrás-Cuesta, Francisco, Sarobe, Pablo, Prieto, Jesús, Lasarte, Juan José
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777173/
https://ncbi.nlm.nih.gov/pubmed/24093105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/864720
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