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Precocious Puberty and Leydig Cell Hyperplasia in Male Mice With a Gain of Function Mutation in the LH Receptor Gene

The LH receptor (LHR) is critical for steroidogenesis and gametogenesis. Its essential role is underscored by the developmental and reproductive abnormalities that occur due to genetic mutations identified in the human LHR. In males, activating mutations are associated with precocious puberty and Le...

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Detalhes bibliográficos
Main Authors: McGee, Stacey R., Narayan, Prema
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776872/
https://ncbi.nlm.nih.gov/pubmed/23861372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2179
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