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Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries

The luteinizing hormone receptor, LHCGR, is essential for fertility in males and females, and genetic mutations in the receptor have been identified that result in developmental and reproductive defects. We have previously generated and characterized a mouse model (KiLHR(D582G)) for familial male-li...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Hai, Lan, McGee, Stacey R., Rabideau, Amanda C., Paquet, Marilène, Narayan, Prema
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706306/
https://ncbi.nlm.nih.gov/pubmed/26040673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.129072
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