Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs

Ozone exposure causes airway hyperreactivity and increases hospitalizations resulting from pulmonary complications. Ozone reacts with the epithelial lining fluid and airway epithelium to produce reactive oxygen species and lipid peroxidation products, which then activate cell signaling pathways, inc...

Full description

Saved in:
Bibliographic Details
Main Authors: Verhein, Kirsten C., Salituro, Francesco G., Ledeboer, Mark W., Fryer, Allison D., Jacoby, David B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776780/
https://ncbi.nlm.nih.gov/pubmed/24058677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075351
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items