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Suppression of Antiviral Innate Immunity by Sunitinib Enhances Oncolytic Virotherapy

The use of lytic viruses to preferentially infect and eliminate cancer cells while sparing normal cells is a promising experimental therapeutic approach for treating cancer. However, the efficacy of oncolytic virotherapy is often limited by two innate immunity pathways, the protein kinase PKR and th...

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Detaylı Bibliyografya
Asıl Yazarlar: Jha, Babal K, Dong, Beihua, Nguyen, Carvell T, Polyakova, Irina, Silverman, Robert H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776628/
https://ncbi.nlm.nih.gov/pubmed/23732991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.112
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