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Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst

[Image: see text] A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.

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Autors principals: Cheung, Chi Wai, Buchwald, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776604/
https://ncbi.nlm.nih.gov/pubmed/23883393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401796v
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