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ATP-Binding Cassette Transporter G1 Intrinsically Regulates Invariant NKT Cell Development

ATP-binding cassette transporter G1 (ABCG1) plays a role in the intracellular transport of cholesterol. Invariant NKT (iNKT) cells are a subpopulation of T lymphocytes that recognize glycolipid Ags. In this study, we demonstrate that ABCG1 regulates iNKT cell development and functions in a cell-intr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sag, Duygu, Wingender, Gerhard, Nowyhed, Heba, Wu, Runpei, Gebre, Abraham K., Parks, John S., Kronenberg, Mitchell, Hedrick, Catherine C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776580/
https://ncbi.nlm.nih.gov/pubmed/23100511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201570
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