Suicidal gene therapy in an NF-κB-controlled tumor environment as monitored by a secreted blood reporter

The nuclear factor-κB (NF-κB) is known to be activated in many cancer types including lung, ovarian, astrocytomas, melanoma, prostate as well as glioblastoma, and has been shown to correlate with disease progression. We have cloned a novel NF-κB-based reporter system (five tandem repeats of NF-κB re...

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Detalhes bibliográficos
Main Authors: Badr, CE, Niers, JM, Morse, D, Koelen, JA, Vandertop, P, Noske, D, Wurdinger, T, Zalloua, PA, Tannous, BA
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776578/
https://ncbi.nlm.nih.gov/pubmed/21150937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.156
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