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Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells

Graft rejection by the immune system is a major cause of transplant failure. Lifelong immunosuppression decreases the incidence of graft rejection; however, nonspecific immunosuppression results in increased susceptibly to infection and cancer. Regulatory T cells (T(regs)), which suppress the activa...

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Hlavní autoři: Sagoo, Pervinder, Ali, Niwa, Garg, Garima, Nestle, Frank O., Lechler, Robert I., Lombardi, Giovanna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776382/
https://ncbi.nlm.nih.gov/pubmed/21593402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002076
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