Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations

Adoptive transfer of ex vivo expanded CD4(+)CD25(+)FOXP3(+) regulatory T cells is a successful therapy for autoimmune diseases and transplant rejection in experimental models. In man, equivalent manipulations in bone marrow transplant recipients appear safe, but questions regarding the stability of...

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Bibliographische Detailangaben
Hauptverfasser: Scottà, Cristiano, Esposito, Marianna, Fazekasova, Henrieta, Fanelli, Giorgia, Edozie, Francis C., Ali, Niwa, Xiao, Fang, Peakman, Mark, Afzali, Behdad, Sagoo, Pervinder, Lechler, Robert I., Lombardi, Giovanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2013
Schlagworte:
Original Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729911/
https://ncbi.nlm.nih.gov/pubmed/23242600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.074088
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