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SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway
Many studies have demonstrated that SIRT1, an NAD(+)-dependent deacetylase, reduces apoptosis in several different cells. However, the role of SIRT1 in apoptosis of disc nucleus pulposus (NP) cells remains unclear. The present study was performed to determine whether degenerative human NP would expr...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776108/ https://ncbi.nlm.nih.gov/pubmed/22990594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9474-y |
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