SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway

Many studies have demonstrated that SIRT1, an NAD(+)-dependent deacetylase, reduces apoptosis in several different cells. However, the role of SIRT1 in apoptosis of disc nucleus pulposus (NP) cells remains unclear. The present study was performed to determine whether degenerative human NP would expr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wang, DaWu, Hu, ZhenMing, Hao, Jie, He, Bin, Gan, Qiang, Zhong, XiaoMing, Zhang, XiaoJun, Shen, JieLiang, Fang, Ji, Jiang, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776108/
https://ncbi.nlm.nih.gov/pubmed/22990594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9474-y
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge