Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia

Global DNA hypomethylation affecting repeat sequences has been reported in different cancer types. Herein, we investigated the methylation levels of repetitive DNA elements in chronic lymphocytic leukemia (CLL), their correlation with the major cytogenetic and molecular features, and clinical releva...

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Autori principali: Fabris, Sonia, Bollati, Valentina, Agnelli, Luca, Morabito, Fortunato, Motta, Valeria, Cutrona, Giovanna, Matis, Serena, Grazia Recchia, Anna, Gigliotti, Vincenzo, Gentile, Massimo, Deliliers, Giorgio Lambertenghi, Bertazzi, Pier Alberto, Ferrarini, Manlio, Neri, Antonino, Baccarelli, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775884/
https://ncbi.nlm.nih.gov/pubmed/20930513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.2.13528
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