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Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia

Global DNA hypomethylation affecting repeat sequences has been reported in different cancer types. Herein, we investigated the methylation levels of repetitive DNA elements in chronic lymphocytic leukemia (CLL), their correlation with the major cytogenetic and molecular features, and clinical releva...

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Detalhes bibliográficos
Main Authors: Fabris, Sonia, Bollati, Valentina, Agnelli, Luca, Morabito, Fortunato, Motta, Valeria, Cutrona, Giovanna, Matis, Serena, Grazia Recchia, Anna, Gigliotti, Vincenzo, Gentile, Massimo, Deliliers, Giorgio Lambertenghi, Bertazzi, Pier Alberto, Ferrarini, Manlio, Neri, Antonino, Baccarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775884/
https://ncbi.nlm.nih.gov/pubmed/20930513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.2.13528
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