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Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumorigenicity
BACKGROUND: T-cell factor (TCF) proteins represent key transcription factors that activate Wnt/β-catenin signaling. We have reported that a pair of TCF-4 isoforms (TCF-4C and TCF-4D) exhibits differential TCF transcriptional activity in hepatocellular carcinoma (HCC) cells, although their structure...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775864/ https://ncbi.nlm.nih.gov/pubmed/23648141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12189 |
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