Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumorigenicity

BACKGROUND: T-cell factor (TCF) proteins represent key transcription factors that activate Wnt/β-catenin signaling. We have reported that a pair of TCF-4 isoforms (TCF-4C and TCF-4D) exhibits differential TCF transcriptional activity in hepatocellular carcinoma (HCC) cells, although their structure...

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Huvudupphovsmän: Tomimaru, Yoshito, Xu, Chelsea Q., Nambotin, Sarah B., Yan, Tao, Wands, Jack R., Kim, Miran
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775864/
https://ncbi.nlm.nih.gov/pubmed/23648141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12189
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