Učitavanje...

Loss of the SxxSS Motif in a Human T-Cell Factor-4 Isoform Confers Hypoxia Resistance to Liver Cancer: An Oncogenic Switch in Wnt Signaling

PURPOSE: Aberrantly activated Wnt/β-catenin signaling is important in hepatocellular carcinoma (HCC) development. Downstream gene expressions involving the Wnt/β-catenin cascade occur through T-cell factor (TCF) proteins. Here, we show the oncogenic potential of human TCF-4 isoforms based on the exp...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Koga, Hironori, Tsedensodnom, Orkhontuya, Tomimaru, Yoshito, Walker, Evan J., Lee, Han Chu, Kim, Kang Mo, Yano, Hirohisa, Wands, Jack R., Kim, Miran
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386968/
https://ncbi.nlm.nih.gov/pubmed/22768190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039981
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!