Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/β-catenin signaling pathway in hepatocellular carcinoma cells

BACKGROUND/AIMS: The canonical Wnt signaling is frequently activated in human hepatocellular carcinoma (HCC). We previously demonstrated that up-regulation of Frizzled-7 receptor (FZD7) in HCC was associated with nuclear accumulation of wild-type β-catenin. Here, we investigated Wnt ligand(s) that m...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Kim, Miran, Lee, Han Chu, Tsedensodnom, Orkhontuya, Hartley, Rochelle, Lim, Young-Suk, Yu, Eunsil, Merle, Philippe, Wands, Jack R
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390890/
https://ncbi.nlm.nih.gov/pubmed/18313787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2007.12.020
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы