Functional consequences of WNT3/Frizzled7-mediated signaling in non-transformed hepatic cells

We have previously demonstrated that WNT3 and Frizzled7 (FZD7) expression levelswere upregulated in hepatocellular carcinoma (HCC) and that they directly interact to activate the canonical Wnt/β–catenin pathway in HCC cell lines. In this study, we investigated the functional consequences of WNT3 and...

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Detalhes bibliográficos
Main Authors: Nambotin, S B, Tomimaru, Y, Merle, P, Wands, J R, Kim, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503290/
https://ncbi.nlm.nih.gov/pubmed/23552403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.31
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