Area-Specific Alterations of Synaptic Plasticity in the 5XFAD Mouse Model of Alzheimer’s Disease: Dissociation between Somatosensory Cortex and Hippocampus

Transgenic mouse models of Alzheimer’s disease (AD) that overproduce the amyloid beta peptide (Aβ) have highlighted impairments of hippocampal long-term synaptic plasticity associated with the progression of the disease. Here we examined whether the characteristics of one of the hallmarks of AD, i.e...

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Détails bibliographiques
Auteurs principaux: Crouzin, Nadine, Baranger, Kevin, Cavalier, Mélanie, Marchalant, Yannick, Cohen-Solal, Catherine, Roman, François S., Khrestchatisky, Michel, Rivera, Santiago, Féron, François, Vignes, Michel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775744/
https://ncbi.nlm.nih.gov/pubmed/24069328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074667
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