Clinical and Immunologic Effects of Intranodal Autologous Tumor Lysate-Dendritic Cell Vaccine with Aldesleukin (Interleukin 2) and IFN-α2a Therapy in Metastatic Renal Cell Carcinoma Patients

PURPOSE: To evaluate the clinical and immunologic outcomes of DC (dendritic cell) vaccine with interleukin (IL)-2 and IFN-α 2a in metastatic renal cell carcinoma patients. EXPERIMENTAL DESIGN: Eighteen consented and eligible patients were treated. Peripheral blood monocytes were cultured ex vivo int...

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Main Authors: Schwaab, Thomas, Schwarzer, Adrian, Wolf, Benita, Crocenzi, Todd S., Seigne, John D., Crosby, Nancy A., Cole, Bernard F., Fisher, Jan L., Uhlenhake, Jill C., Mellinger, Diane, Foster, Cathy, Szczepiorkowski, Zbigniew M., Webber, Susan M., Schned, Alan R., Harris, Robert D., Barth, Richard J., Heaney, John A., Noelle, Randolph J., Ernstoff, Marc S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775650/
https://ncbi.nlm.nih.gov/pubmed/19622576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3240
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