Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

PURPOSE: To evaluate CD4(+)CD25(+)FOXP3(+) T regulatory cells (T(REG)) and associated immune-regulatory pathways in peripheral blood lymphocytes (PBL) of metastatic renal cell carcinoma (mRCC) patients and healthy volunteers. We subsequently investigated the effects of immunotherapy on circulating T...

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Main Authors: Schwarzer, Adrian, Wolf, Benita, Fisher, Jan L., Schwaab, Thomas, Olek, Sven, Baron, Udo, Tomlinson, Craig R., Seigne, John D., Crosby, Nancy A., Gui, Jiang, Hampton, Thomas H., Fadul, Camilo E., Heaney, John A., Ernstoff, Marc S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485261/
https://ncbi.nlm.nih.gov/pubmed/23118856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046600
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