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Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer

Alternative splicing is a fundamental step in regulation of gene expression of many tumor suppressors and oncogenes in cancer. Signalling through the Ras-MAPK and PI3K-mTOR pathways is misregulated and hyperactivated in most types of cancer. However, the regulation of the Ras-MAPK and PI3K-mTOR sign...

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Hlavní autoři: Siegfried, Zahava, Bonomi, Serena, Ghigna, Claudia, Karni, Rotem
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775402/
https://ncbi.nlm.nih.gov/pubmed/24078813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/568931
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