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Transformation by v-Src: Ras-MAPK and PI3K-mTOR Mediate Parallel Pathways

An increase in the level of active, GTP-bound Ras is not necessary for transformation of chicken embryo fibroblasts (CEF) by v-Src. This suggests that other Ras-independent pathways contribute to transformation by v-Src. To address the possibility that activation of phosphatidylinositol-3-kinase (PI...

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Autores principales: Penuel, Elicia, Martin, G. Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC25360/
https://ncbi.nlm.nih.gov/pubmed/10359590
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