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In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cells
IgA nephropathy (IgAN) patients have elevated serum levels of immune complexes consisting of IgA1 with galactose-deficient hinge-region O-glycans (Gd-IgA1) and anti-glycan IgG. These immune complexes deposit in the kidney and activate mesangial cells. To confirm that the activity of these immune com...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775378/ https://ncbi.nlm.nih.gov/pubmed/24052934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinim.2012.08.002 |
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