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Pyrin- and CARD-only Proteins as Regulators of NLR Functions

Upon activation Nod-like receptors (NLRs) assemble into multi-protein complexes such as the NODosome and inflammasome. This process relies upon homo domain interactions between the structurally related Pyrin and caspase-recruitment (CARD) domains and adaptor proteins, such as ASC, or effector protei...

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Hlavní autoři: Le, Hongnga T., Harton, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775265/
https://ncbi.nlm.nih.gov/pubmed/24062743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00275
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