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Pyrin- and CARD-only Proteins as Regulators of NLR Functions
Upon activation Nod-like receptors (NLRs) assemble into multi-protein complexes such as the NODosome and inflammasome. This process relies upon homo domain interactions between the structurally related Pyrin and caspase-recruitment (CARD) domains and adaptor proteins, such as ASC, or effector protei...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775265/ https://ncbi.nlm.nih.gov/pubmed/24062743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00275 |
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