A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children

HIV-1 persists in a latent state in resting CD4(+) T lymphocytes of infected adults despite prolonged highly active antiretroviral therapy (HAART). To determine whether a latent reservoir for HIV-1 exists in infected children, we performed a quantitative viral culture assay on highly purified restin...

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Pubblicato in:	J Clin Invest
Autori principali:	Persaud, Deborah, Pierson, Theodore, Ruff, Christian, Finzi, Diana, Chadwick, Karen R., Margolick, Joseph B., Ruff, Andrea, Hutton, Nancy, Ray, Stuart, Siliciano, Robert F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10749578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9006
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