Resting CD4(+) T Lymphocytes but Not Thymocytes Provide a Latent Viral Reservoir in a Simian Immunodeficiency Virus-Macaca nemestrina Model of Human Immunodeficiency Virus Type 1-Infected Patients on Highly Active Antiretroviral Therapy

Despite suppression of viremia in patients on highly active antiretroviral therapy (HAART), human immunodeficiency virus type 1 persists in a latent reservoir in the resting memory CD4(+) T lymphocytes and possibly in other reservoirs. To better understand the mechanisms of viral persistence, we est...

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Main Authors: Shen, Anding, Zink, M. Christine, Mankowski, Joseph L., Chadwick, Karen, Margolick, Joseph B., Carruth, Lucy M., Li, Ming, Clements, Janice E., Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152116/
https://ncbi.nlm.nih.gov/pubmed/12663799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4938-4949.2003
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