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A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children

HIV-1 persists in a latent state in resting CD4(+) T lymphocytes of infected adults despite prolonged highly active antiretroviral therapy (HAART). To determine whether a latent reservoir for HIV-1 exists in infected children, we performed a quantitative viral culture assay on highly purified restin...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Persaud, Deborah, Pierson, Theodore, Ruff, Christian, Finzi, Diana, Chadwick, Karen R., Margolick, Joseph B., Ruff, Andrea, Hutton, Nancy, Ray, Stuart, Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10749578/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9006
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