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Physical Motif Clustering within Intrinsically Disordered Nucleoporin Sequences Reveals Universal Functional Features

Bioinformatics of disordered proteins is especially challenging given high mutation rates for homologous proteins and that functionality may not be strongly related to sequence. Here we have performed a novel bioinformatic analysis, based on the spatial clustering of physically relevant features suc...

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Hlavní autoři: Ando, David, Colvin, Michael, Rexach, Michael, Gopinathan, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774778/
https://ncbi.nlm.nih.gov/pubmed/24066078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073831
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