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Physical Motif Clustering within Intrinsically Disordered Nucleoporin Sequences Reveals Universal Functional Features

Bioinformatics of disordered proteins is especially challenging given high mutation rates for homologous proteins and that functionality may not be strongly related to sequence. Here we have performed a novel bioinformatic analysis, based on the spatial clustering of physically relevant features suc...

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書誌詳細
主要な著者: Ando, David, Colvin, Michael, Rexach, Michael, Gopinathan, Ajay
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774778/
https://ncbi.nlm.nih.gov/pubmed/24066078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073831
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